List of largest biotechnology and pharmaceutical companies

The following is a list of the independent biotechnology companies listed on a stock exchange (as indicated) with current market capitalization of at least US$10 billion, in decreasing order.

The list does not include biotechnology companies that are currently owned by, or a part of, larger pharmaceutical groups.

Rankings

Rank[N 1] Company Largest Market Cap (USD billions) Market Cap in 2020 (USD billions)[1] Market Cap in 2019 (USD billions) Market Cap in 2018 (USD billions) Market Cap in 2017 (USD billions) Market Cap in 2016 (USD billions)[2][3] Market Cap in 2015 (USD billions)[4] Market Cap in 2014 (USD billions)[5] Market Cap in 2013 (USD billions)
1 Johnson & Johnson[P]
NYSE: JNJ
399.9 (Dec 2020) 399.99 385.0 346.1 375.4 314.1 284.2 277.8 258.3
2 1 Roche[P]
SIX: ROG
291.1 (Dec 2020) 291.12 281.1 209.3 216.7 192.1 234.7 258.5 240.3
3 2 Pfizer[P]
NYSE: PFE
310.5 (Jul 2000) 208.11 216.7 259.7 215.9 196.3 199.3 205.4 196.0
4 1 Novartis[P]
NYSE: NVS
275.2 (Jul 2015) 202.09 240.0 200.0 196.7 170.5 206.1 229.8 195.0
5 1 Merck & Co.[P]
NYSE: MRK
232.9 (Dec 2019) 201.80 232.9 205.8 153.3 164.3 147.6 166.9 146.5
6 Moderna[P]
Nasdaq: MRNA
201 (Sep 2021) 68.5 45.0 -
7 Abbott Laboratories[P]
NYSE: ABT
190.4 (Dec 2020) 190.44 153.5 126.8 99.3 56.4 67.0 67.9 59.3
8 2 AbbVie[B]
NYSE: ABBV
196.2 (Jan 2018) 182.27 130.9 146.3 154.4 100.2 96.8 104.1 83.8
9 Novo Nordisk[P]
NYSE: NVO
161.9 (Dec 2020) 161.99 137.1 111.9 131.2 92.6 153.9 125.4 -
10 2 Eli Lilly & Co[P]
NYSE: LLY
158.3 (Dec 2020) 158.30 126.9 125.6 93.0 80.9 93.4 76.6 57.0
11 3 Bristol-Myers Squibb[P]
Nasdaq: BMY
137.8 (Dec 2020) 137.85 105.0 85.0 100.3 98.2 114.8 97.6 87.2
12 4 Amgen[B]
Nasdaq: AMGN
145.8 (Dec 2019) 129.79 144.6 128.8 126.2 108.9 122.5 93.1 78.7
13 2 AstraZeneca[P]
LSE: AZN
130.8 (Dec 2019) 129.44 130.8 96.2 87.9 68.8 85.8 88.9 74.6
14 4 Sanofi[P]
NYSE: SNY
151.3 (Sep 2014) 120.66 63.5 108.4 108.2 101.8 111.8 138.1 142.0
15 2 GlaxoSmithKline[P]
LSE: GSK
174.9 (May 2006) 90.15 117.2 94.8 87.9 93.3 97.6 128.9 129.6
16 1 Stryker Corporation[P]
NYSE: SYK
88.8 (Dec 2020) 88.81 78.5 58.6 58.0 45.1 34.7 35.7 28.4
17 2 Zoetis[P]
Nasdaq: ZTS
76.6 (Aug 2020) 75.97 63.2 41.4 35.1 26.4 23.8 21.6 16.3
18 3 Gilead Sciences[B]
Nasdaq: GILD
179.6 (Jun 2013) 71.93 82.3 81.6 93.6 96.6 145.8 109.0 78.4
19 6 Daiichi Sankyo[P]
Nasdaq: DSNKY
45.3 (Dec 2019) 63.92 45.3 22.7 27.5 35.3 38.8 33.2 28.7
20 1 Vertex Pharmaceuticals[B]
Nasdaq: VRTX
78.9 (Jul 2020) 61.33 56.3 42.2 37.9 18.3 31.0 28.7 17.4
21 4 Bayer[P]
FWB: BAYN
129.0 (Mar 2015) 58.12 80.1 63.1 101.9 85.3 103.2 113.2 117.4
22 2

Takeda Pharmaceutical[P]
Nasdaq: TAK

61.5 (Dec 2019) 56.78 61.5 52.9 40.2 45.6 47.8 37.5 34.3
23 1 Illumina[B]
Nasdaq: ILMN
56.0 (Jul 2019) 53.51 48.2 44.1 40.2 39.4 35.4 28.6 25.7
24 2 Regeneron Pharmaceuticals[B]
Nasdaq: REGN
61.4 (Aug 2015) 52.52 41.2 40.3 40.4 39.3 56.5 42.0 27.4
25 3 Biogen[B]
Nasdaq: BIIB
111.7 (Mar 2015) 38.66 54.7 63.5 67.4 61.6 68.3 79.7 66.1
26 2 Alexion Pharmaceuticals[P]
Nasdaq: ALXN
47.0 (Jul 2015) 33.52 24.3 21.7 26.7 27.4 43.1 36.7 26.0
27 3 Seagen[B]
Nasdaq: SGEN
38.2 (Oct 2020) 34.44 19.5 13.8
28 1 Astellas[P]
TYO: 4503
40.6 (Dec 2015) 27.52 32.7 23.8 29.3 25.7 40.6 35.8 27.6
29 4 Genmab[B]
Nasdaq: GMAB
25.9 (Nov 2020) 25.53 14.5 10.6 10.8 10.8 8.8 3.8 2.6
30 1 Eisai Pharmaceutical[P]
TYO: 4523
37.3 (Dec 2016) 19.93 21.5 23.0 24.5 37.3 28.8 30.2 28.7
31 Alnylam Pharmaceuticals [P]
Nasdaq: ALNY[6]
23.36 18.5 24.0 21.0 16.0 -
32 Incyte[P]
Nasdaq: INCY
31.2 (Mar 2017) 19.25 18.8 13.5 18.3 15.4 10.6 7.3 4.6
33 BioMarin[P]
Nasdaq: BMRN
24.0 (Jul 2015) 16.03 15.2 15.1 18.3 20.4 13.8 12.9 10.8
34 BeiGene [P]
SSE: 688235
33.14 (Nov 2021) 34.20 27.00 26.00 24.03 10.28 8.33 4.45 1.20
35 1 BioNTech[P]
Nasdaq: BNTX
44.07 62.52 19.62 7.68 -
36 1 Horizon Therapeutics[P]
Nasdaq: HZNP
18.06 (Dec 2020) 14.2 11.6 9.3 5.0 6.5 2.8 2.0 -
37 1 10x Genomics[7][P]
Nasdaq: TXG
17.54 11.2 -
38 1 Jiangsu Hengrui Medicine[P]
SSE: 600276
41.17 59.98 93.42 60.85 30.53 30.54 16.79 15.10 -
39 1 Elanco[P]
NYSE: ELAN
13.06 (Nov 2020) 11.2 -
40 1 Celltrion[P]
KRX: 068270
23.03 (2021) 40.90 19.22 -
41 1 Viatris[P]
Nasdaq: VTRS
18.50 (Dec 2021) -
42 1 Sun Pharma[P]
NSE: SUNPHARMA
27.15 (2021) 19.01 -
43 1 Divi's Laboratories[P]
NSE: DIVISLAB
15.29 (Nov 2021) -
44 1 Dr. Reddy's Laboratories[P]
NSE: DRREDDY
10.94 (2021) 11.75 -
45 1 Cipla[P]
NSE: CIPLA
10.21 (Dec 2021) 10.19 -

Footnotes

  1. The change is the companies' relative position in this list, compared to their relative position in the prior year; i.e, an increase would be moving closer to rank 1 and vice versa
  • B – Biotechnology company
  • P – Pharmaceutical company

See also

References

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