There are so many people driving and so many who don't drive safely even for other drivers, much less for people not in cars, that statistically it's impossible to avoid not running into a dangerous situation in the places where cars interact with people running, walking, or wheeling.

We can try traffic calming and reducing city speed limits, but people driving will still speed (making collisions with cars and people more dangerous), run stop signs and lights and not yield or even look for pedestrians (making street crossing dangerous).

Since it seems impossible to change the minds and habits of every person driving, it seems more effective to reduce the number of interactions between people in cars and everyone else doing anything else. We have sidewalks for pedestrians (though they still get hurt and killed even in marked street crossings). We have "bike" lanes for people wheel (bikes, electric scooters, motorized wheelchairs, etc) though because of the way many are built and protected there's often still a lot of interaction between people driving and people wheeling.