Silicone is often a problem because it sticks to silicone better than anything else. Over time movement will cause silicone to peel off of one side of any joint and stubbornly stick to the other side and be a p i t a to remove. Quad is much better. Quad is a version of polyurethane sealant or PL. These sealants are difficult to apply and messy and they never really cure so they sort of stay gummy but they have really good performance as sealers

Siliconized latex or. Siliconized acrylic is a very different thing. Paintable. Water clean up. Stays flexible better than regular latex

Good old regular latex caulk my brand is white lightning is still a very good option for anything that's going to be painted over. It holds paint well and it's very inexpensive and easy to apply

There's also butyl rubber mostly used on metal like gutters and copolymer sealant like lexel. Very messy very difficult to apply but can provide really good performance for the right application