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chrisdh79 OP t1_iwc2j42 wrote

From the article: Blood transfusions are an important way to replace lost blood, often saving lives in the worst possible circumstances. But not everyone can get the procedure. Some patients with rare blood group types don’t meet the requirements. But what if they could use blood grown in a lab?

The National Health Service (NHS) in the U.K. announced on Monday that it has started a clinical trial where researchers will be administering laboratory-grown red blood cells to patients. Notably, this is the first time ever that red blood cells grown in a lab will be given to another person as part of a blood transfusion trial.

The study––called the RESTORE trial––is a joint research initiative between the NHS Blood and Transplant (NHSBT) and the University of Bristol, as well as various researchers at the University of Cambridge.

In a YouTube video from NHS, University of Bristol researcher Ash Toye explains that RESTORE is a clinical trial set up to assess whether lab-grown red blood cells are similar, or possibly even better, than a donor’s own blood cells produced inside the body.

“We’re hoping that because they’re so freshly made and ready to go that they’ll be better. If that’s true, then this will be a world first because effectively we’ve taken a cell produced in the donor and we’ve put them into a volunteer who is not related to the donor and they’ve been matched,” he said.

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SH4DOWSTR1KE_ t1_iwc8lw8 wrote

Synth blood could be a game changer but I'm wondering if they are going to make just a synthetic type O or are they going to try and go deeper to match phenotypes?

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FuturologyBot t1_iwcghtl wrote

The following submission statement was provided by /u/chrisdh79:


From the article: Blood transfusions are an important way to replace lost blood, often saving lives in the worst possible circumstances. But not everyone can get the procedure. Some patients with rare blood group types don’t meet the requirements. But what if they could use blood grown in a lab?

The National Health Service (NHS) in the U.K. announced on Monday that it has started a clinical trial where researchers will be administering laboratory-grown red blood cells to patients. Notably, this is the first time ever that red blood cells grown in a lab will be given to another person as part of a blood transfusion trial.

The study––called the RESTORE trial––is a joint research initiative between the NHS Blood and Transplant (NHSBT) and the University of Bristol, as well as various researchers at the University of Cambridge.

In a YouTube video from NHS, University of Bristol researcher Ash Toye explains that RESTORE is a clinical trial set up to assess whether lab-grown red blood cells are similar, or possibly even better, than a donor’s own blood cells produced inside the body.

“We’re hoping that because they’re so freshly made and ready to go that they’ll be better. If that’s true, then this will be a world first because effectively we’ve taken a cell produced in the donor and we’ve put them into a volunteer who is not related to the donor and they’ve been matched,” he said.


Please reply to OP's comment here: https://old.reddit.com/r/Futurology/comments/yv2dwf/scientists_begin_trials_for_transfusions_of/iwc2j42/

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thewordof_dog t1_iwcgu1z wrote

"Could be a game changer". Or, "Is currently an impractical boondoggle"

Sounds great until another scientist examines the details.

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joeg26reddit t1_iwcnzj0 wrote

Anyone else looking forward to “Cruelty Free Gravy” (trademark pending)

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a3lt t1_iwdsbyu wrote

Most likely much deeper. Here is some more info on the deeper types that you mention. Essentially, there are slightly less important antigens that blood cells have, and for most transfusions we don't care about them. However, for people who need repeated transfusions (due to a disorder or illness), they have to be careful about those other antigens, because those patients can build up antibodies to them with repeated exposure. Those patients are more difficult to find compatible blood for, and lab grown blood could make it much easier to obtain the required type.

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