Submitted by tonymmorley t3_za6yyq in Futurology
redrightreturning t1_iylaaw8 wrote
Reply to comment by TheGoodFight2015 in Vaccine prompts HIV antibodies in 97 per cent of people in small study by tonymmorley
No, no one was exposed to HIV, that would obviously be unethical. The way the drug worked was that it was supposed to mimic some of the HIV proteins and cause your body to make antibodies to those. The study was also experimenting with a novel mechanism of injecting the vaccine, using an electrical sock (for lack of a better word) to facilitate the uptake of the vaccine.
*shock, not sock
Louisville_Jason t1_iyli7cj wrote
I'm sorry...using a what?
bootymix96 t1_iyllkh9 wrote
Pretty sure they meant electric shock, which is a phenomenon known as electroporation (Sardesai & Weiner 2011). According to Sardesai and Weiner (2011), electroporation involves a series of “brief electric pulses” administered in conjunction with DNA-based injected vaccines to boost the vaccine’s uptake by our cells through “transient and reversible permeabilization of the cell membrane.”
Ojiambo (2021) discusses the administration process in the context of COVID-19 vaccinations. The DNA-based vaccine is injected, a separate hand-held device is used to generate the electrical impulses at the injection site immediately afterwards, and those impulses induce electroporation and allow the vaccine molecules to break through our cell membranes and increase our immune system response to the vaccine (Ojiambo 2021).
techno156 t1_iylqg4w wrote
Interesting that electroporation works on people. I only expected it to work on bacteria, or to be unsafe for humans due to the whole heart and brain thing.
Just_Another_Wookie t1_iym025p wrote
As long as the path of the current doesn't cross the brain or heart, it's all good!
dromaeovet t1_iym1uqt wrote
Electroporation is one of the principles by which Dolly the sheep was cloned :) They basically took cell contents that could eventually become the sheep, used electroporation to insert it into a recipient cell, and then implanted that in the surrogate.
redrightreturning t1_iymfsy4 wrote
Yes this is exactly what I meant! Thank you for adding your knowledge.
I will say the shocks hurt pretty bad. The first time they told me it would be like getting punched in the arm. Well it turns out I had never been punched before so I had no idea what to expect and almost passed out. Subsequent times I was ready for it and it wasn’t as bad.
MicrosoftOSX t1_iylkd89 wrote
e-sock. like e-mail, but a sock
JebediahKerman3999 t1_iylo026 wrote
If you put a sock over the vaccine, when the virus grabs it it only has the sock
MicrosoftOSX t1_iylovh3 wrote
It is especially effective around the end of the year
teraflux t1_iylm1jq wrote
I use SOCKS 5, great for pirating things
redrightreturning t1_iymfyqo wrote
Woops, I meant an electrical shock. A user below did a good job explaining what the process is and why they used it.
TheGoodFight2015 t1_iyvqox9 wrote
Sorry I didn’t mean exposed in the study, I meant exposed at some other period in your life. But then I see you said they believe they weren’t exposed, so my post was pretty confusing. So you’re basically wondering how well the drug worked for you personally. I’m just still confused because wouldn’t they provide data for the efficacy in the experimental group of that trial? Or are you saying it’s still ongoing?
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