The majority of testing done on animals is Toxicology testing. At what concentrations do you start seeing harmful effects. Animal testing isn't used nearly as much in Efficacy tests. I worked in a lab that did Toxicology testing. A lot of drugs don't do much and it's testing new formulas for drugs already commonly on the market. But there are also a lot of cancer drugs and opiods that end up having a lot of unexpected effects. Also you end up with small companies that have Lawyers and investors that have everything riding on their one drug they have and they are willing to try and make any shortcuts they can to make sure that drug gets to market. I worry about those companies if the FDA opens a path that won't be tested with animals.