It's not even close. These people will go knowing they can't come back. You're only talking about getting lost. Space involves far more pernicious dangers. It's a 9 month trip just to get there, and then years before you eventually die or a method of return travel arrives. We don't know how Mars gravity or radiation will affect the human body long-term. You can't go outside ever again. Can't see a blue sky or watch a bird fly. In modern terms, you'll never again access the internet. It's possible that minor injuries are likely to be death sentences. And the money involved is astronomical compared to building wooden ships. Essentially, the psychological stress will be unlike anything humans have encountered to date.

I strongly suggest looking at astrophysicists' discussions about life on Mars and travel to Mars for a more complete understanding of the possibilities and challenges.