Submitted by tonymmorley t3_zio6ed in Futurology
Comments
Pieniek23 t1_izs4551 wrote
Groundbreaking for sure. Wishing her all the best.
ThrillSurgeon t1_iztuadj wrote
This is great news.
senorbozz t1_izslqvk wrote
Sometimes you scroll through Reddit and just let out a FUCK YEAH when you read a headline.
jkj2000 t1_iztonvr wrote
Exactly! What are the further possibilities if you can do this on one “area”, can it be used on other “defects”?
keryia111 t1_izu9rv7 wrote
Please search radiolab and crispr. They did a story about 8 years ago, it’s two parts and very interesting.
I didn’t realize we were already using crispr in people, but it does have the possibility of changing healthcare forever.
jkj2000 t1_izuauhy wrote
Thanks 🙏
My daughter has Vitiligo, and uses methotrexate so this is very interesting if this DNA defect could be rewritten, to avoid the side effect of the chemotherapy!
tonymmorley OP t1_izrukfy wrote
Nonbinary_Tea t1_izt5j2b wrote
Tf..awesome site.
Robbob533 t1_izuq24r wrote
My son had Leukemia diagnosed in March 2020. He got Car-T treatment which is similar to crispr. His cancer was gone within a month. It’s amazing what science and technology is capable of. So far 2.5+ years and still no trace of the cancer coming back. Even his own immune system which was eradicated as a part of the treatment is starting to show signs of coming back. God bless this patient and hopefully they will get back to a normal life like my son has been able to do.
drgeta84 t1_izwcppe wrote
My mother had this done for her acute lymphoblastic leukemia. She has had leukemia twice, She went through normal chemo and a bone marrow transplant first time. Was a really rough 3-4 months but went into remission. Second time she was put into a trial for the CAR-T cells. It was 2-3 months of out patient and she only had a little bit of a headache and some slight nausea. Insane how different it was and she’s still in remission. There were 15 people in the trial and only 5 survived as it has a really aggressive autoimmune issues with random organs. It’s early days but it was mind blowing how easy it was compared to chemo.
FuturologyBot t1_izrwxxf wrote
The following submission statement was provided by /u/tonymmorley:
>"A 13-year-old girl whose leukaemia had not responded to other treatments now has no detectable cancer cells after receiving a dose of immune cells that were genetically edited to attack the cancer" — Experimental CRISPR technique has promise against aggressive leukaemia
>
>"A teenager with aggressive leukaemia now has no detectable cancer cells after becoming the first person to receive a treatment involving a new kind of CRISPR called base editing. However, it will not be clear for some years whether she will remain free of the condition."
Please reply to OP's comment here: https://old.reddit.com/r/Futurology/comments/zio6ed/experimental_crispr_technique_has_promise_against/izruhh2/
pjvincentaz t1_izuvfzq wrote
Amazing. Would it be dangerous to have children after this procedure because your DNA has been modified? Probably a dumb question, but this technology is so far beyond me I can barely comprehend it.
-Ch4s3- t1_izvci06 wrote
It’s not a germ line edit so your sex cells are not effected, but they’re probably already cooked by the chemotherapy.
2Balls2Furious t1_izuyy90 wrote
Does anyone actually know what the “new technology” being referenced in this article is supposed to be? Is it a new gene-editing method being applied to CAR-T cells? Both CAR-T therapy and CRISPR-Cas9 technology have been around for some time, so I’m confused what’s new here.
Phoenix5869 t1_izw0ezw wrote
I assume it hasn't been used for that specific type of cancer before
[deleted] t1_j039bvm wrote
[removed]
tonymmorley OP t1_izruhh2 wrote
>"A 13-year-old girl whose leukaemia had not responded to other treatments now has no detectable cancer cells after receiving a dose of immune cells that were genetically edited to attack the cancer" — Experimental CRISPR technique has promise against aggressive leukaemia
>
>"A teenager with aggressive leukaemia now has no detectable cancer cells after becoming the first person to receive a treatment involving a new kind of CRISPR called base editing. However, it will not be clear for some years whether she will remain free of the condition."