my guess is because it's not really that novel. organoids, retroviruses, and this type of work in general have been around for a minute now. but also, in my personal opinion, the impact factor of journals is a bunch of bs where famous PIs can submit trash now that they've submitted one good paper they're still riding the coat tails on 20 years later. so as long as the methods look good and the experiments are legit, i wouldn't worry too much about what journal it was published in.