OneLostOstrich t1_jcnh9y7 wrote
Fascinating work. I'm surprised that there aren't more questions.
Can you share the latest in the process of restoring nerve damage or encouraging nerves to grow to a tissue or implanted material?
What about encouraging growth of collagen producing cells that decline as we age? Also, encouraging satellite cell division and promotion of apoptosis in cells that are not functioning normally.
UniversityofBath OP t1_jd3m06e wrote
Hello! Thank you for some great questions. I'll break them down in my response;
- nerve regeneration: I actually did do some work on this. I grew nerve cells on my materials and tested the network by sending a signal from one end and seeing whether it would be received on the other end of the network (spoiler: it did!). Many different groups are working on this area and it could mean great things for example for Alzheimer's patients but also for people who have suffered nerve damage in other ways.
- collagen production: most of my materials are designed to recreate the space around the cells. Collagen proteins can also be 'woven' into this space and we can attract cells to that space to carry on the process (it is essentially what I try to do but with more than just collagen). Regarding the ageing tissue: it's an area that both the healthcare and the beauty industry are interested in and whoever gets there first will be inundated with requests i'm sure!
- apoptosis: Yes there are ways that we can induce cell death. Normally this is done by tuning the delivery method so none of the healthy cells die in the process. This type of targeted delivery aligns well with incorporation of drugs for example.
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