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motominiman t1_j5l4o1s wrote

There's been a few studies about the benefits nicotine can have for dopamine related conditions like ADHD and Parkinson's. Do you think there's a possibility that the benefits of just nicotine (not tobacco) could outweigh the negatives for these kinds of conditions? How do the costs and benefits of nicotine compare to costs and benefits of drugs like adderall and L-Dopa?

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BrownNWG OP t1_j5l9l89 wrote

>There's been a few studies about the benefits nicotine can have for dopamine related conditions like
>
>ADHD
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> and
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>Parkinson's
>
>. Do you think there's a possibility that the benefits of just nicotine (not tobacco) could outweigh the negatives for these kinds of conditions? How do the costs and benefits of nicotine compare to costs and benefits of drugs like adderall and L-Dopa?

Caveat, the people answering in the room are not experts in ADHD or Parkinson’s and their relationship to smoking. We will try to track down better answers later and respond directly.

Our initial thoughts are that nicotine has similar properties to stimulant medications, like Adderall. Stimulants can actually help smokers with ADHD quit smoking. Research on costs and benefits can be challenging because of the healthcare system and due to ethical considerations (if you have a medication that works you would need a good reason to give someone nicotine instead in a drug trial).

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cepheid22 t1_j5mr9ij wrote

That is very interesting as schizophrenia is linked with nicotine use and ADHD. The vast majority of schizophrenics smoke at some time in their lives, many citing that it helps with symptoms though the research is inconclusive. Schizophrenia and ADHD have high comorbidity rates. Not to mention that psychosis can be a symptom of Parkinson's. Ah, that wiley dopamine!

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Drona2019 t1_j6b36bf wrote

Do you still experience delusions and hearing voices while on anti-psychotics?

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