I'll turn the heat up to 60 F overnight to protect the pipes; wind pulls heat from buildings, too, and the only time I came close to frozen pipes was subzero temps + wind. My usual overnight setting is 50F.
In wind, a layer of petroleum jelly on your face can help; and wear one of your cloth face masks from Covid.
Frostbite is fast in low temps with wind.
Fleece tights under your pants; anything other than cotton is warmer than jeans, I can't find affordable wool pants these days.
Wear wool & fleece instead of cotton.
Pull the curtains; glass is a poor insulator and will let the cold in.
A hot water bottle or metal water bottle with hot tap water keeps you cozy.
Your pets' feet can get too cold; don't keep them out long.
I always have emergency supplies in my car, including socks, mittens, hat, blanket, water, jar of hard candy, granola bars, fleece. Severe weather is hard on cars.
I hate going out in subzero weather, so I won't.

Give handwarmers, mylar emergency blankets, chocolate, and dunkin or other gift cards to homeless folks; the shelters will be bursting, some of them won't go.