Physical Address:
Thomas P. "Tip" O'Neill Federal Building
10 Causeway Street, Room 247
Boston, MA 02222

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https://travel.state.gov/content/travel/en/passports/get-fast/passport-agencies/boston.html

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Our passport agencies and centers offer two types of appointments: Life-or-Death Emergency Service and Urgent Travel Service. You must call us to make one of these appointments. Follow the steps on how to apply on each agency and center webpage.

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To apply at this passport agency, you must meet all of the following requirements:
Make an appointment by calling 1-877-487-2778 or 1-888-874-7793, 8:00 a.m. to 10:00 p.m. ET, Monday through Friday. Our appointment line is closed on the weekend and on federal holidays. We do not charge a fee to make appointments.
Be traveling internationally within 14 calendar days.
Be able to show printed proof of international travel (such as your flight itinerary, hotel reservation, cruise tickets, or international car insurance).
Pay the $60 expedite fee in addition to the regular application fees.
Note: your appointment must be within 14 calendar days of your international travel. If you need a foreign visa, the date of your appointment must be within 28 calendar days of your international travel.
If you have a life-or-death emergency, please see Life-or-Death Emergencies. If you don't meet the requirements for an appointment, please see Where to Apply for other options.

You must make an appointment to apply at a passport agency.
To make an appointment, you must call 1-877-487-2778 or 1-888-874-7793 (TDD/TTY). Se habla español. Be sure to keep track of the appointment confirmation number and the check-in instructions you will receive by email from the National Passport Information Center. You will need this information on the day of your appointment.