I worked and drive through there pretty often. The Brown/RISD area tends to be pretty safe, but common sense travel is always advised.

Winters are a bit harsh, so bundle up. I tend to still wear shorts and a T in the winter, but but your mileage may vary. I would say prepare for a lot of hills and perhaps snow boots for the winter hike. College Street and Waterman Street tend to be some of the steeper but more frequently travelled roads. Just watch out for cars since. Keep to the pavement and follow the lights.