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Wow.

“The drug is a breakthrough in diabetes treatment, experts say, but it won’t be cheap. It’s delivered intravenously on 14 consecutive days, per Medpage Today’s Nicole Lou. Each day’s treatment will cost $13,850, for a total of $193,900.”

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With a pricetag like that this isn't exactly uplifting news.

Are they clear if it is type 1 or type 2 preventative?

"Your pancreas is encased in a coffin made of fat, so it's shutting down" has much cheaper alternative options.

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It’s for type 1, and it may delay its onset for a couple of years.

Based on a trial of 76 people, with a delay of a few years and no mention of possible side effects, and you’re expected to pay nearly $200,000?

I couldn’t see in the report. Did all those at high risk go onto develop diabetes?

Type 1 here - pretty much. They did some tests on identical twins and found that in almost all cases, once the first twin develops T1, the second follows within a few months (edit: I had misremembered this)

2 years might not make much of a difference to folks like me who developed it as adults (I was 30), but it’s significant for young children.

Having T1 significantly impact your routine, and it’s pretty difficult to manage especially for very young kids (think: toddlers) who can’t truly understand what’s going on, and very much struggle with diabetes management - and parents too! Also, even two years could lessen the long term risks associated with T1 (think: retinopathy, kidney disease, diabetic foot, etc.)

well fuck, so you are getting it anyway. what difference does it make

Thanks. Had a re-read of the article and saw the bit about checking the autoantibodies in the participants and were in the early stages of diabetes.

Hi. This is a random add on about the identical twin thing. Did you mean in the study that this article was about? Or do you mean in general, because it’s only 30-50% of the other identical twin who goes on to develop DM1 after the other has it (90% if it’s type2)

You are right, I had misremembered it! Thanks for fact-checking :)

As someone with diabetes, it could be a huge fucking difference for someone who can even ducking speak. Extremely dirty that it’s $200k.

No prob. There was something niggling at the back of my head that type 2 was higher than type 1 in identical twins both getting it, so I needed to check it myself.