I think the thing you'll struggle witht he most is the weather. It can get very cold here, and we can get gobs of snow. OTOH, you're within reach of Boston and an hour away from Northampton (about as liberal an area as you're going to find in MA). If you like outdoors, the white mountains are just north, the berkshires are just west. Plenty of outdoors stuff.

Worcester is a mixed bag politically, so you'll find both ends of the spectrum, but you'll be able to find comfortable spaces to be yourself and socialize.

But just like any area, making social connections can be hard for some, easy for others.