Submitted by Raul_Endy t3_10vfweb in askscience
ZookeepergameOpen824 t1_j7i95jy wrote
Smog or other gases that are inhaled can enter the systemic blood stream and cause oxidative stress to the circulatory system or blood vessels. The particles causing damage to the lining of the vessels or the sacs in the lungs will initiate the inflammatory response and cause cellular mediators such as platelets & fibrin, to heal the damaged wall. This causes the vessels to narrow or form plaques overtime and can obstruct blood flow to the heart/brain. A piece of the plaque can also rip off and travel to the brain and obstruct blood flow that way as well.
LachoooDaOriginl t1_j7kbpvm wrote
so it makes a bunch of blood clots waiting to happen? damn
Proof_Device_8197 t1_j7ogotx wrote
The vessels go into ‘repair mode’ initiated by inflammation due to the oxidative stress insults described above. Going into inflammatory repair mode response is essentially the body’s way of laying down scar tissue in the blood vessels. This entire process repeats over and over again until you’ve essentially decreased the integrity and function of the vessels themselves, leading to cardiac diseases.
[deleted] t1_j7kgcb8 wrote
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[deleted] t1_j7iowtj wrote
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