I have Celiac. There is such an increase in risk of some viral infections that the Pneumonia vaccines are recommended regardless of age (normally reserved for healthy people after age 65). Risk of some cancers is elevated - pancreatic, stomach, intestinal. Worse, some vaccines don’t seem to work as well (particularly Hep A in children). Heart disease is also elevated with an adjusted risk ratio of 1.27 after adjusting for other things like lifestyle choices (though no-one is sure why). Overall its about a 5 yr reduction in life expectancy - which is on par with other major immune diseases. And there is no medical treatment available. Only medical advice is to avoid a particular protein which is prevalent literally everywhere while there is evidence this strategy - even when done effectively - has limited success in managing symptoms. (Rather ironically, the one symptom most impacted by the GF diet is weight loss - people who actually need to eat GF tend to gain 10 to 20 lbs rather quickly. It is designed to be the exact opposite of a weight loss diet).