The_RealKeyserSoze t1_j94iqkm wrote on February 19, 2023 at 4:27 AM

There are a lot of signals controlling inflammation and fever. But one of the simplest explanations is cortisol. Fevers tend to spike at night when cortisol levels are low but subside in the morning when cortisol levels are highest.

Javlington t1_j95ol87 wrote on February 19, 2023 at 1:09 PM

Is this the thing where the immune system evolved to become more active at night because then we rest anyway - no resources needed for walking around and hunting etc.? (which would then be achieved through cortisol levels)