You might be interested in this paper: https://www.frontiersin.org/articles/10.3389/fgene.2011.00100/full

Outlines in vivo studies in mice showing how Ras zygosity effects tumour identity differently based on the type of mutation they've got. While Ras knockouts seem to make fetuses unviable, Ras Gain-of-function seems to still permit viability, but also confers shorter lifespans because of tumours.

A lot of Ras mutations are acquired from what i know, with different mutations being linked more to certain organs because of the nature of carcinogens that organ is exposed to. So I don't know if it's super worth looking deeper into heredity of this sort of thing, even if its very cool.