Submitted by OryuSatellite t3_11uhvmh in askscience
h3rbi74 t1_jcq4wsa wrote
Reply to comment by OryuSatellite in How does immunity to larger internal parasites such as worms work? by OryuSatellite
I think it’s not that the adults are immune to worms, it’s that they have the capacity to carry a small to moderate parasite load without severe health effects, which is not the case for tiny babies. Economics of farming says treat the babies but leave the adults be.
(Also it really depends on which worms you’re talking about, because they each have different life cycles, but in some there is no way to truly eliminate them. I’m a vet tech but haven’t worked with sheep since undergrad so would need to brush up on them, but in adult dogs for example, common roundworms migrate out of the intestines and encyst themselves in a dormant state, then can be activated later by certain triggers, including pregnancy. I’ve been taught that 99% of puppies have roundworms, even if the mother had a negative fecal test. So we routinely aggressively deworm all puppies, and then treat adults on an as-needed case-by-case basis. https://www.merckmanuals.com/home/multimedia/image/life-cycle-of-the-toxocara-roundworm )
OryuSatellite OP t1_jcq6umw wrote
My vet does describe it as immunity, for what it's worth, and my understanding is that adults with "immunity" are expected to have relatively low parasite load, not only higher tolerance of parasite load. But certainly it only means relative immunity, not absolute immunity. Immune response that attacks eggs and freshly hatched parasites as the previous answer described (and as in the very cool video) seems to make sense.
ETA: I also have farm cats, and the cats get wormed every three months without fail for their whole lives (on advice of the same vet) so no expectation of immunity there. But I don't think it's economics of pets versus farm animals that is the reason for the difference, although avoidance of anthelmintic resistance is certainly a factor for the sheep.
h3rbi74 t1_jcq7cfh wrote
As long as the understanding is relative/low load and not absolute/zero load, I think we’re 100% on the same page! :)
Viewing a single comment thread. View all comments