Submitted by E-C-A t3_121p52k in askscience
wildfire393 t1_jdnij8h wrote
Reply to comment by LordRobin------RM in Why does tetanus vaccination lasts longer than influenza vaccination? by E-C-A
There's some dropoff over time even against the same strain, but there's also better immune response after more exposures. The first COVID shot was two doses because testing showed a better immune response for two doses at a certain concentration several weeks apart, rather than a larger dose one time.
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