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penicilling t1_irbasko wrote

Reply to comment by [deleted] in Why do some antihistamines make you sleepy? by [deleted]

>Are 1st gen safer ? wich do you reccommend ?

While I cannot recommend a specific medication for anyone (an interview, physical exam, and review of current and past medical issues is necessary before any such recommendations), in general, second-generation antihistamines such as cetirizine, fexofenadine, and loratadine are the first-line recommendations for symptoms of allergic rhinitis, as the side effects (such as sedation) are much less pronounced than the first-generation medications.

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[deleted] OP t1_irbg8ou wrote

[deleted]

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penicilling t1_irbn6c0 wrote

>Not just that, the second generation antihistamines are generally first line for anything where an actual antihistamine would be required,

This is generally true. The exception would be in patients for whom oral medications are not optimal, such as those with nausea and vomiting or with severe allergic reactions -- some 1st generation antihistamines are available in parenteral formulations, whereas, to the best of my knowledge, 2nd generation antihistamines are only available in oral form.

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GamblingTheory t1_irbk18u wrote

Fexofenadine is a third generation antihistamine and thus in many countries not freely available without prescription.

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