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TripleXAfro t1_irbwxnt wrote

Reply to comment by shaftshaftner in Why do some antihistamines make you sleepy? by [deleted]

I took 450mg in a sitting , I remember passing out for an hour and waking up with the proportions of everything being extremely messed up and a weird shine on everything. I didn't have a negative experience which is interesting.

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TripleXAfro t1_irbx9aa wrote

Unlike drinking grapefruit juice and then Consuming 100mg of dmx. That was the worst experience I've ever had.

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YoureSpecial t1_irc3fao wrote

Grapefruit juice fucks all kinds of drugs up. Can make them last longer, lose effectiveness, activate the active ingredients all at once instead of over time, inhibit active ingredients, make some drugs toxic, etc.

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Blakut t1_irewtfg wrote

Yeah what is up with that?

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YoureSpecial t1_irf13av wrote

It’s true of all citrus to some degree, but grapefruit’s effects are waaaaaay more pronounced. It’s some sort of flavonoid or something. I can’t remember just now.

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