Well… sort of. While encoding proteins is arguably the most important and certainly the most visible function of the genome, there are parts that code for RNA that does not get translated into protein. These and other non-coding segments actually make up the majority of the human genome, and many of them play important roles. Though it is true that almost all those roles support the expression or regulation of proteins in some indirect way.

Also, a gene moving to a different locus can actually make a big difference, because the way it is expressed and regulated can change, even if it codes for the same protein.