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tsunamisurfer t1_ishsh54 wrote

Reply to comment by Kandiru in When it's said 99.9% of human DNA is the same in all humans, is this referring to only coding DNA or both coding and non-coding DNA combined? by PeanutSalsa

Originally though, the reference genome was that of the first sequenced human genome, which I believe belonged to J Craig Venter.

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Kandiru t1_isim3ny wrote

Actually there were two competing approaches at the beginning. Venter did sequence himself with shotgun sequencing, while the high fidelity BAC sequencing with Sanger sequencing was done on a range of different individuals spanning the genome.

So the first version of the reference was a mixture of them all.

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