heresacorrection t1_ivgtoop wrote
Reply to comment by FellowConspirator in If the Human Genome Project represents a map of the genome of a few individuals, why is this relevant to humans as a whole if everybody has different genetics? by bjardd
On average we expect an individual to have millions of variants that differ from the reference. Most of which are inconsequential (i.e. not malignant).
In addition, relative to the reference, the variability is dependent on your origin.
"Consistent with the out-of-Africa model of human origin, the number of variant sites per genome is highest among Africans (∼5 million variants) compared with individuals of East Asian, European, or South Asian ancestry (∼4.0–4.2 million variants) "
ivan_drago27 t1_ivh98dx wrote
Such a good note to add on the out-of-Africa model, thank you for including that. Been a few years since I actively studied this stuff and that made me want to dig into some theory again.
Viewing a single comment thread. View all comments