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Kyrthis t1_ivy4kvx wrote

Reply to comment by pokerchen in Why do individuals with Turner's syndrome (XO sex chromosomes) not have ovaries? by KissMyAFF

That is how it works for autosomes. Sex chromosomes, however, work with a single copy always. The Y is always alone in a cell. In females, only one X is being transcribed due to random X inactivation, which is what creates Barr Bodies.

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pokerchen t1_ivzezk9 wrote

There are special mechanisms that permit certain DNAs to still function within the Barr Bodies. I'll share this article with you as a quick Google search: https://phys.org/news/2016-07-scientists-untangle-barr-body-inactive.html

Learned about how BBs are not silent while chatting with a professor in 2006. I suspect we don't know the exact details just yet, but could do a proper literature search. (Note: expertise is structural biology/biophysics. Almost went into epigenetics instead.)

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