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Duckboy_Flaccidpus t1_ix5zeq1 wrote

Reply to comment by lambertb in Do NSAIDs reduce neuroinflammation? by One-Garden-1294

All this seems to fly in the face of something like Bayer aspirin that says it helps to reduce heart attacks and can be prescribed a small dose daily to aid in continued blood flow.

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15MinuteUpload t1_ix6bo7m wrote

Aspirin has a different mechanism compared to other NSAIDs and does in fact have well-studied benefit in heart disease protection and clot risk. That being said, that benefit is likely less than previously believed due to more recent studies and evidence and it does not come without risks, but it certainly exists.

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lambertb t1_ix67fdw wrote

It’s complicated. Aspirin is an NSAID, but not Al NSAIDS are the same with respect to adverse effects. Aspirin has cardiac benefits because it’s an anticoagulant. The same basic effect is why NSAIDS can cause bleeding strokes. I can’t explain all the mechanisms. I just know it to be true.

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jaldihaldi t1_ix6ojvo wrote

Though ibuprofen might cause green in high blood pressure patients?

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55peasants t1_ix6y51o wrote

Asprin inhibts COX-1 more than COX-2, last time I read up on it, this was the theory on the difference on cardiovascular safety

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