I don't take nasaids, but I do take pot, the edible kind, for severe back pain. And it is illegal in my state. If someone told me I would have increased cardiac risk for doing so, I wouldn't hesitate to continue. Until you've had debilitating pain, you have no idea what someone is willing to do. If I got cardiac problems? I figure they would probably put me out of my pain sooner, rather than living with it for year after year.