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Alwayssunnyinarizona t1_iz3dmgy wrote

Great answer. The serotypes, in a way, are a phenotype - one that is "seen" by the host's antibody response. Like a negative image, perhaps. The genotype codes for that "phenotype" in a way that we haven't quite figured out yet (ie, there aren't commonly PCR tests, or MALDI data for serotypes, but there are groups working on them almost tirelessly).

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dave-the-scientist t1_iz50sxy wrote

We actually can do serotyping by sequence for a bunch of bacterial pathogens. Neisseria meningitidis, for one. Pasteurella multocida for another. Those are two I've done in the past couple months.

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