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attentionhordoeuvres t1_j2jojei wrote

No. And even if they did involve infectious material (again, they don’t), the tests don’t involve putting that material in your body. You would take a sample from your body and mix it with other substances ex vivo to observe some kind of reaction.

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drz420 t1_j2jr2ou wrote

Most labs are drawn into a handful of generic negative-pressure test tube types which contain various blood stabilizers. These are then taken to a lab where the blood is mixed with different reagents for testing. Even if infectious materials were involved in testing (which is not the case), none of the testing materials are present in the tube used for the lab draw. In addition, blood only moves into the collection bottles because they typically use negative pressure to pull blood in.

The only way testing could transmit something like HIV is if a needle was re-used between patients, but most venipuncture needles have locking safety mechanisms to prevent re-use.

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Greyswandir t1_j2jt42r wrote

No. The tests generally use antibodies to test for your antibodies. The only antigen would come from you. And as noted by others, even if the test did contain antigen, it would 1) likely not be infectious on its own and 2) not enter your body.

The type of test you’re thinking of is a lateral flow immunoassay or dipstick test. They perform a type of test (assay in fancy scientist speak) called a sandwich assay. The strip is prepared with three things:

  1. a loading pad that includes an antibody which binds to the target analyte (the thing you are testing for). We will call this antibody A. For the type of test you describe, an antibody test for HIV, the analyte is human anti-HIV antibodies. The Antibody-A’s are bound to something that generates a visible color, often a metal particle such as gold.
  2. A test line, which is a line we’ve drawn across the strip and chemically glued another set of Antiboy-A’s down so they are stuck to the strip
  3. A control line which has a second type of antibody (Antibody-B) which will bind to Antibody-A

When we add a sample to the loading pad, it will start flowing down the strip. If analyte is present it will bind the loose Antibody-A’s and become colored as it flows down the strip. When it hits the test like those Antibody-A’s will bind the analyte too. So if analyte is present we form a “sandwich” with two Antibody-A’s as the bread (one bound to a colored marker and one bound to the strip) and the analyte as our filling. If there’s no analyte (or if there is and there are extra Antibody-A’s) they will get grabbed by the Antibody-B’s at the control line.

PS: Antigen not Antigene. Antigen just means something an antibody binds to. Doesn’t have to be (and usually isn’t) anything genetic.

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Ganymede25 t1_j2qywyl wrote

Absolutely not. The biological liquid (blood or saliva usually) is taken from you and then exposed to an antibody testing material outside of your body. Antigens that react to antibodies are never injected into your body.

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