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llfre t1_j38xqle wrote

Being pedantic, but I wouldn't frame it this way. The pathologies in those conditions aren't that insulin levels are too high (barring accidental/intentional overdose), but a deficient effect.

There are feedback mechanisms that titrate secretion to response in cases of insulin resistance, therefore prolonged hyperglycaemia promotes insulin secretion.

Type 1 is typically due to a deficiency of insulin for various reasons.

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Temporary_turbulance t1_j3bscau wrote

I am aware of the mechanisms of these conditions, but insulin levels can still be high even if blood glucose is in range and stable. If an individual (diabetic or not) is insulin resistant, surely their “fasting” insulin will be higher than someone who is not insulin resistant.

I’m asking how this excess insulin is removed from the body when it is not used.

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