I had an interesting experience with appendicitis. When I first felt it I didn't feel it in my lower right abdominal quadrant, I felt it right below my navel. At first I thought it was just something like constipation. Then by the next day it migrated to the LRQ.

I wondered why I had this experience and the answer was that the nerve for that region joins the spine at just below the navel. So at first I felt it at the spinal region then as the region around my appendix got more inflamed the pain sensation moved to that region.