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being_interesting0 t1_j4tyanf wrote

Here is a paper that suggests epigenetics plays a large role. https://www.nature.com/articles/s41598-019-54447-w

It is true that mammal size is correlated to heart rate, and both are correlated to lifespan. Most mammals get about 1 billion heart beats. Humans have managed to beat this by being more social (supporting our elders in pre-medicine societies) and then using medical technology to really overcome natural entropy.

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Aus_scientist t1_j4upta9 wrote

Similarly, here is a new paper from Sinclair Lab also suggesting this (more specifically loss of epigenetic info). Came out a few days ago and people are still dissecting it.https://www.cell.com/cell/pdf/S0092-8674(22)01570-7.pdf

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