[This paper in Cell (pdf)](https://www.cell.com/cell/pdf/S0092-8674(22)01530-6.pdf) examines the role of endogenous retroviruses and senescence and was discussed in the latest podcast from "This Week in Virology."

During the podcast, they also discussed other research showing that, in mice, repeated blood transfusion from young mice to elderly mice over extended periods of time produced rejuvenating effects. Thinks like improved strength, thickening of cartilage, etc.

There is a very long way between that research and increased lifespan in humans, but my opinion is that it's worth considering the possibility we'll eventually get there. Or if not lifespan, per se, then better health through the lifespan (health span).