I'm sorry to say, you are going to have a pretty hard time in Baltimore. You probably want to consider someplace directly adjacent to the university. Something that hasn't been mentioned here yet is how things get in bad weather. Be prepared for a lot of standing water when it rains (poor drainage, large deep puddles, etc.). Snow removal and salting isn't that great either. The closer you are to campus, the better; even 3 or 4 blocks after a snow may be impassable. Also, there are tons of potholes, poorly patched roads and uneven sidewalks. There are a few buildings directly in the JHU-HW neighborhood that would probably be your best choice.

Because of the age of many of the buildings, you will find that many commercial establishments will be inconvenient; e.g. one or two steps to enter or just inside, narrow entries, etc.

Hampden is about 1-1.5 miles away. That's a great neighborhood for bars/restaurants if that's within your range. Charles Village also has quite a few cool spots.

You will almost certainly find that locals in those neighborhoods do not have an issue with individuals with disabilities and are very open minded/welcoming.