I wouldn't do a neighborhood east of 83 unless you want to pay tolls or don't mind adding 10 or 15 minutes to the commute. Maybe longer in the evenings.

I used to live west of 83, and my commute was better/more predictable (although I was going to Rockville). Now I live east and it is easily 15 or 20 minutes longer in the evenings since I drive through the city to get home.