If you don't mind a lot of religious backdrop with a near explicit evil Catholic vs good Protestant try Safehold by David Weber. It's a sci-fi series where the last colony ship was sent off into deep space with orders to go dark and emit nothing for a thousand years to escape the aliens that killed the rest of humanity. However, there was a revolt among the leadership and instead of knowledge being preserved it was destroyed with an oppressive controlling church put in charge. Now a robot is charged with ending the church in order to revive humanity's tech base to take the fight back to the stars. We are 10 books in and the key struggle is still against the not Catholic church.

Still, it does a good wide angle lens at different regions, some religious disagreements, scale and effects of the conflicts.

First book {{Off Armageddon Reef}}