lbs21 t1_j3cl3bg wrote on January 7, 2023 at 4:35 PM

Reply to comment by theggman_ in [OC] Estimated toxicity of various common drugs (Sources and explanation in the comments) by theggman_

Thanks for posting the source. Weird that you're having trouble posting links, though. Regardless, I was hoping you might be able to help me find the info inside of a source. I was surprised to see that the TI of fentanyl was 7x that of alcohol (given the fear mongering), and I couldn't find the ED-50 on the DEA's website. It's possible I missed it - could you identify the paragraph on the DEA's website that talks about the ED-50 of fentanyl? I'm kind of surprised they'd give out that info, to be honest.

I noticed that the ED-50 of fentanyl was italicized - does that mean it is perhaps not listed in the source provided?

theggman_ OP t1_j3cmu34 wrote on January 7, 2023 at 4:46 PM

oh yeah i forgot to add, i have taken most of the active doses from psychonaut wiki.
Whilst it is obviously not a reputable source, they usually have pretty accurate information and finding reputable source for recreational doses is pretty hard

lbs21 t1_j3cpzve wrote on January 7, 2023 at 5:07 PM

That's very relevant and important information; good to know. Thank you for your prompt reply.

[deleted] t1_j3cqxxd wrote on January 7, 2023 at 5:13 PM

[removed]

lbs21 t1_j3clqmk wrote on January 7, 2023 at 4:39 PM

I thought this might be it, but it doesn't match the data - FDA says fentanyl is about 100x more potent than morphene. Assuming this matches the ED (a big assumption), the ED of fentanyl would be .0024 mg/kg (or 1/100th of morphene), and the TI to be 1.25. But such a low TI can't be right... can it?