I can only think of a couple off the top of my head and the first is debatable as to how it falls on the comedic/drama scale.

In Big Fish Edward meets the love of his life and comments that people are right about time standing still, but they don't tell you it compensates by moving extra fast to catch up and she leaves before he ever has a chance to ask who she is or even talk to her.

In Cube 2: Hypercube a couple of the group members end up in a trap room with accelerated time and wind up aging into skeletons while having sex.