I think there's a fair point some cities have a very real, and weird obsession with the lifestyle/vibe/setting/whatever and that carries into media.

NY/LA have been like that forever. Boston has been coming on strong the past 25 years or so. It gets pretty tiring when a movie is as much about the LA-ness or NYC-ness of the setting as it is about whatever the movie is nominally about.

Also, there are a decent number of movies set in LA that are just Hollywood doing a circlejerk, inside baseball depiction of how great Hollywood is (even if they try to hide it). That's not necessarily LA's fault, it just happens to be big hub of where movies are made. Those movies would be insufferable if they were set in Toledo too.