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coilycat t1_j533fm5 wrote

I used to be on a monoamine oxidase inhibitor (MAOI), as an antidepressant. Maybe she could take one of those!

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americancorn t1_j5f6cav wrote

Actually the opposite i’m p sure! Most ppl have working monoamine oxidase A.

The few ppl w a genetic mutation of MAOA like it seems OP has, have trouble getting rid of serotonin, norepinephrine, etc. In these cases, too much of them leads to aggression, angry-reactions, etc. Whereas most ppl take MAOIs in order to increase those chemicals (by stopping the MAO enzymes from working)

I thought the same as u but got curious and fell deep into wiki lol

TLDR “Special” MAOA gene 🧬 —> mutation of an MAO enzyme so it doesn’t work properly. In effect comparable to taking too many MAOIs from birth.

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Mysterious-Mist t1_j53rejs wrote

Yes and she has to stay off aged cheese , wine etc.. hope she has the self control.

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coilycat t1_j5457b7 wrote

Oddly, enough, fava beans are also a no-go, even though other beans are fine. As a vegan, I had no problem avoiding the cheese & sausage.

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bliss_ignorant t1_j5ksc0i wrote

There are safer mao(a) inhibitors called rima's (reversible inhibitors of monoamine oxidase a) they deactivate it rather than destroying both mao a&b. mao(b) is the one that processes tyramine, so dietary restrictions aren't as necessary with rima's.

i have know idea if rimas are as effective as irreversible maoi's for deppresion

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