There are some cool spots West of Broad in South Philly. There are also some shitholes full of dead-enders as well.

Spots to Try:

Second District

South House

ARS (Though it does skew to a more family crowd)

South Philly Taproom

La Lorna

Black Cat

Taproom on 19th

Jiminy Cricket's

The Republican (RIP)

Spots to Avoid:

The Station

SK Bar

17 Snyder Chinese

Hennessy (I like this spot but, might not be what you're looking for)

624 Lounge (I think this was shut down by L&I)