Have you heard of consequences? And patterns? Meaning is omnipresent, it always was and always will be. "Meaninglessness" is an utter impossibility. If the distance between the Sun and the Earth was half of what it is or twice what it is, we would not be having this conversation over the Internet right now. You cannot make the distance between the Sun and the Earth "meaningless". Every little detail of this universe (past, present, future) makes it this universe and not a very similar story (e.g. a tiny little detail is different in Act 1 of Romeo and Juliet so in the end Romeo and Juliet lived happily growing old together).

Scientists, poets, painters and sculptors use meaning. Our eyes and ears and brains use meaning. Because clues are everywhere whether detectives exist or have not evolved from primordial ooze yet or nuked themselves into extinction.