Frank's Buffalo Chicken pizza gets my vote. It's not necessarily a unique idea, most places have it. But they absolutely knock it out of the park. It's also relatively cheap considering most place's Buffalo Chicken pizza falls into their "Gourmet Pizza" bucket, which usually means $25 for an 8-cut pie. Also worth noting that the rest of Frank's menu is pretty blah, but if you're looking for a life-changing Buff Chix this is definitely it.

Second in my mind is Monte Cello's Steak Onion Ranch pizza. These are easily the last 2 pizzas I'd want to eat if the world was coming to an end.