Viewing a single comment thread. View all comments

supertexter t1_j7h55es wrote

Reply to comment by Ok_Lifeguard_6508 in Analysis showed that 65.6% of women who took extra Vitamin D gave birth naturally. The study analysed results from the MAVIDOS trial which involved 965 women being randomly allocated an extra 1,000 International Units (IU) per day of vitamin D during their pregnancy or a placebo. by Wagamaga

Haven't done the math, but about an 8 percentage point difference and a sample size of 1000, that seems significant to me

24

SaltZookeepergame691 t1_j7h61lf wrote

It’s significant (and the 95% CI indicates it is reasonably so), but this is a post hoc analysis of an outcome they already ‘knew’, in a trial that already had many outcomes, making this result at pretty high risk of being a chance false positive. This is probably why they don’t give actual p values - the findings are hypothesis generating, not confirmatory.

28

supertexter t1_j7hbikw wrote

That sounds reasonable indeed. Interesting result though, the future will tell us more.

1

TravisJungroth t1_j7htx36 wrote

Rounded off.

A: 579/1000
B: 656/1000
p=0.0002

Like the other comment said, remember it's post hoc.

1