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Pro-Karyote t1_j7w865m wrote

Reply to comment by TinFoilHeadphones in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico

For daily prophylactic use, it’s 81mg for all body weights (though the actual definition of low-dose aspirin is anything less than 100mg per day - 81mg is traditionally the dose for historical reasons).

Current Aspirin Guidelines

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tjeulink t1_j7wl80m wrote

Historical reasons on medicine dosages? Now im interested haha

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Pro-Karyote t1_j7wp06j wrote

It has to do with a unit of measurement we don’t currently use for dosing medications, called a grain. The full dose of aspirin was 5 grains, which is about 325mg. The low dose was a quarter of the full dose, so 1.25 grains (which is roughly 81mg). That was the dose that was on formulary, and since it falls within the low-dose range and it was the dose available, it stuck.

Brief overview of aspiring dosing history

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TinFoilHeadphones t1_j7xgrnp wrote

Oh, that explains. I thought he said such a specific number as 81mg because of some calculations. I couldn't understand why such a weird number.

(I don't live in the USA, so measurements here are different)

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