JKyyy_ t1_j8199uz wrote on February 10, 2023 at 9:49 PM

Reply to comment by ctorg in Scientists have identified the brain structures responsible for compulsive drug-seeking behaviours due to repeated use of cocaine by identificating the structures involved and neural pathways activated with repeated exposure to the drug by giuliomagnifico

I am writing my thesis on this exact topic currently and I wanted to say this exact thing. We roughly know that dopamine is released in these areas as a response to reward/reward predicting stimuli and that dopamine is also involved in a lot of regulatory activity. We know it affects cordination, motivation, emotion regulation etc etc. Knowing this and then thinking about what is the best way to fix a dopamine misfunction (If there is one?, May not be the case) are two seperate things ESPECIALLY, when this system responds to SOOO many different forms of stimuli. Currently I would say a holistic approach (Lifestyle changes, therapy, maybe a medicinal treatment aswell (ie. Methylphenidate (Ritalin) seem to be potential approaches to look at). Deciding what is the best and why and for who is really hard