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hippydog2 t1_j9s6dgj wrote

maybe it's just me, but that does sound like a major break thru?

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OneWorldMouse t1_j9sitkg wrote

Knowing the different ways neurons die and preventing their deaths are giant leaps.

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habeus_coitus t1_j9s8qtb wrote

Let’s wait until the results have been replicated. Parkinson’s research got majorly burned by that somewhat recently.

edit: got it wrong

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Standard_Yogurt_1460 t1_j9sb3ti wrote

Parkinson's too? I thought it was Alzheimer's.

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habeus_coitus t1_j9t9ci4 wrote

Ah crap you’re totally right, I got them mixed up. I guess I’ll blame it on Alzheimer’s, if only fake research had cured it by now.

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Darkhorseman81 t1_j9swtfp wrote

Excess S-Nitrosylation blocks it's function in most cases. Mutation would be a rare exception.

We've know this for a while, but they have just shown an extra mechanism by which it happens.

It's why nitrogen pollution from exhaust fumes is linked to parkinsons.

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accidental_snot t1_j9vf290 wrote

The earth's atmosphere is 80% nitrogen. What does it matter if it's in exhaust? Bonded with something to make some toxic molecule?

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Apprehensive_Ad1744 t1_j9vpujw wrote

Atmospheric nitrogen just nitrogen, N2, which is relatively inert.

Nitrogen in exhaust are nitrogen oxides, namely NO and NO2, which are quite toxic.

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eruborus t1_j9vrc1f wrote

It's research seeking to confirm a hypothesis. It needs to be replicated in mammalian cell line and then in an animal model. Drug development and clinical trials therafter. Bench to bedside in 15-20 years. Hard to say if is a breakthrough before that...ask the Alzheimers researchers.

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